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An adaptation of Dr. Seuss's 1954 children's book, "Horton Hears a Who" is about an imaginative elephant (Jim Carrey) who hears a cry for help coming from a tiny speck of dust floating through the air. Suspecting there may be life on that speck and despite a surrounding community that thinks he has lost his mind, Horton is determined to help. Carell voices the mayor of Who-ville, a distinguished figure of a very small size, too small to be seen by the elephant's eyes.